OVEREXPRESSION OF MELANOCORTIN 2 RECEPTOR ACCESSORY PROTEIN 2 (MRAP2) IN ADULT PARAVENTRICULAR MC4R NEURONS REGULATES ENERGY INTAKE AND EXPENDITURE

Objective: Melanocortin 2 receptor accessory protein 2 (MRAP2) has a critical role in energy homeostasis.Although MRAP2 has been shown to regulates a number of GPCRs involved in metabolism, the key neurons responsible for the phenotype of gross obesity in MRAP2 deficient animals are unclear.Furthermore, to date, all the murine MRAP2 models involve

With the advantages of large working space, low cost Ready To Eat Foods (chilled) and more flexibility, industrial robots have become an important copyright in intelligent manufacturing.Due to the low rigidity of robotic milling systems, cutting vibrations are inevitable and have a significant impact on surface quality and machining accuracy.To imp